Genome Editing

Expert study


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With the aid of genome editing methods it is possible to modify or remove gene sequences in a targeted manner, as well as to precisely incorporate new material into the genome. Through the application of the Clustered Regularly Interspaced Short Palindromic Repeats (or CRISPR) method, which was only introduced a few years ago, it is now possible to carry out such modifications relatively efficiently and with a high degree of precision on bacteria, plants, animals and human beings. This new method of genetic molecule editing is already being widely applied in research and is giving rise to considerable expectations. Initial practical applications for plants already exist, and these have drawn attention to certain issues relating to regulation. In the field of medicine, efforts aimed at developing somatic gene therapy or xenotransplantation, which in the past had encountered difficulties or were found to be impractical, are now entering the realms of possibility. Furthermore, the debate on intervention in the human germline has been reopened.

Organisation

Project duration

November 2017 to spring 2019

Project mandataries

Direction: Dr. Erich Griessler, Institut für Höhere Studien (IHS), Vienne

Project group:

  • Alexander Lang (Coordination du projet), Institut für Höhere Studien, Vienne
  • Sandra Karner et Prof. Armin Spök, Interdisziplinäres Forschungszentrum für Technik, Arbeit und Kultur (IFZ); Graz
  • Prof. Michael Fuchs et Prof. Lukas Kaelin, Katholische Privatuniversität Linz
  • Prof. Malte Gruber et Andrea Sommer, Université de Lucerne

Supervisory group

  • Prof. Alberto Bondolfi, Prof. em. Université de Lausanne; membre du comité de TA-SWISS
  • Prof. Toni Cathomen, Institut für Transfusionsmedizin und Gentherapie, Universitätsklinikum Freiburg i.Br.
  • Prof. Daniel Gygax, Institut für Chemie und Bioanalytik, Fachhochschule Nordwestschweiz FHNW; Vorsitzender der Begleitgruppe
  • Dr. Dominic Hoepfner, Novartis Institutes for BioMedical Research, Basel  
  • Thomas Müller, Schweizer Radio und Fernsehen SRF, membre du comité de TA-SWISS
  • Dr. Benno Röthlisberger, Medizinische Genetik, Kantonsspital Aarau
  • Pfr. Dr. sc. agr. Otto Schäfer, Schweizerischer Evangelischer Kirchenbund SEK
  • Franziska Schwab, Kleinbauern-Vereinigung, Bern
  • Prof. Giatgen Spinas, Prof. em. Universitätsspital Zürich, membre du comité de TA-SWISS
  • Prof. Franziska Sprecher, Institut für Öffentliches Recht, Universität Bern
  • Prof. Bruno Studer, Institut für Agrarwissenschaften, ETH Zürich, 

Project management TA-SWISS

Dr Adrian Rüegsegger, TA-SWISS (E-Mail)

What more is there to know about the project

Documentation (see German or French project side)

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